Neuropathological and behavioral features of an APP/PS1/MAPT (6xTg) transgenic model of Alzheimer’s disease

Neuropathological and behavioral features of an APP/PS1/MAPT (6xTg) transgenic model of Alzheimer’s disease

Abstract Alzheimer's disease is associated with various brain dysfunctions, including memory impairment, neuronal loss, astrocyte activation, amyloid-β plaques, and neurofibrillary tangles. Transgenic animal models of Alzheimer's disease have proven to be invaluable for the basic research...

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Bibliographic Details
Main Authors:	Sung Hyun Tag, Baeksun Kim, Jinhee Bae, Keun-A Chang, Heh-In Im
Format:	Article
Language:	English
Published:	BMC 2022-06-01
Series:	Molecular Brain
Subjects:	6xTg Alzheimer's disease Cognitive impairment Social behavior Anxiety Depression
Online Access:	https://doi.org/10.1186/s13041-022-00933-8

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