Truncated vitronectin with E-cadherin enables the xeno-free derivation of human embryonic stem cells

Abstract Human embryonic stem cells (hESCs) have unique abilities that enable their use in cell therapy, disease modeling, and drug development. Their derivation is usually performed using a feeder layer, which is undefined and can potentially cause a contamination by xeno components, therefore ther...

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Bibliographic Details
Main Authors: Tereza Souralova, Daniela Hulinova, Michal Jeseta, Pavel Ventruba, Ales Hampl, Irena Koutna
Format: Article
Language:English
Published: Nature Portfolio 2023-09-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-023-42236-5