HIV-1 Tat Upregulates the Receptor for Advanced Glycation End Products and Superoxide Dismutase-2 in the Heart of Transgenic Mice

Cardiovascular disorder (CVD) is a common comorbidity in people living with HIV (PLWH). Although the underlying mechanisms are unknown, virotoxic HIV proteins, such as the trans-activator of transcription (Tat), likely contribute to CVD pathogenesis. Tat expression in mouse myocardium has been found...

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Bibliographic Details
Main Authors: Alaa N. Qrareya, Nason S. Wise, Emmanuel R. Hodges, Fakhri Mahdi, James A. Stewart, Jason J. Paris
Format: Article
Language:English
Published: MDPI AG 2022-10-01
Series:Viruses
Subjects:
Online Access:https://www.mdpi.com/1999-4915/14/10/2191