Advances in chondroitinase delivery for spinal cord repair
Chondroitin sulfate proteoglycans (CSPGs) present a formidable barrier to regrowing axons following spinal cord injury. CSPGs are secreted in response to injury and their glycosaminoglycan (GAG) side chains present steric hindrance preventing the growth of axons through the lesion site. The enzyme c...
Main Authors: | , |
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Format: | Article |
Language: | English |
Published: |
IMR Press
2022-06-01
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Series: | Journal of Integrative Neuroscience |
Subjects: | |
Online Access: | https://www.imrpress.com/journal/JIN/21/4/10.31083/j.jin2104118 |