Advances in chondroitinase delivery for spinal cord repair

Chondroitin sulfate proteoglycans (CSPGs) present a formidable barrier to regrowing axons following spinal cord injury. CSPGs are secreted in response to injury and their glycosaminoglycan (GAG) side chains present steric hindrance preventing the growth of axons through the lesion site. The enzyme c...

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Bibliographic Details
Main Authors: Yuting Wei, Melissa R. Andrews
Format: Article
Language:English
Published: IMR Press 2022-06-01
Series:Journal of Integrative Neuroscience
Subjects:
Online Access:https://www.imrpress.com/journal/JIN/21/4/10.31083/j.jin2104118