Cerebral white matter lesions and regional blood flow are associated with reduced cognitive function in early-stage cognitive impairment

BackgroundDifferences in the extent of cerebral white matter lesions (WML) and regional cerebral blood flow (rCBF) in early-stage cognitive impairment (ESCI) contribute to the prognosis of cognitive decline; however, it is unclear precisely how WML and rCBF affect cognitive decline in ESCI.Objective...

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Main Authors: Takeshi Kuroda, Kenjiro Ono, Motoyasu Honma, Miki Asano, Yukiko Mori, Akinori Futamura, Satoshi Yano, Mizuki Kanemoto, Sotaro Hieda, Yasuhiko Baba, Masahiko Izumizaki, Hidetomo Murakami
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-02-01
Series:Frontiers in Aging Neuroscience
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Online Access:https://www.frontiersin.org/articles/10.3389/fnagi.2023.1126618/full