Self-Redirection of Metabolic Flux toward Squalene and Ethanol Pathways by Engineered Yeast

Self-Redirection of Metabolic Flux toward Squalene and Ethanol Pathways by Engineered Yeast

We have previously reported that squalene overproducing yeast self-downregulate the expression of the ethanol pathway (non-essential pathway) to divert the metabolic flux to the squalene pathway. In this study, the effect of co-production of squalene and ethanol on other non-essential pathways (fuse...

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Bibliographic Details
Main Authors: Robina Manzoor, Maqbool Ahmed, Naveeda Riaz, Bushra Hafeez Kiani, Ullah Kaleem, Yasmeen Rashid, Ali Nawaz, Muhammad Umer Farooq Awan, Hooria Khan, Umera Imtiaz, Yasir Rasheed, Imdad Kaleem, Aamir Rasool
Format: Article
Language:English
Published: MDPI AG 2020-02-01
Series:Metabolites
Subjects:
<i>saccharomyces cerevisiae</i>
engineered promoters
repressible promoters
squalene
fusel alcohol
ethanol
Online Access:https://www.mdpi.com/2218-1989/10/2/56

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https://www.mdpi.com/2218-1989/10/2/56

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