Early vigabatrin augmenting GABA-ergic pathways in post-anoxic status epilepticus (VIGAB-STAT) phase IIa clinical trial study protocol

Early vigabatrin augmenting GABA-ergic pathways in post-anoxic status epilepticus (VIGAB-STAT) phase IIa clinical trial study protocol

Abstract Background Nearly one in three unconscious cardiac arrest survivors experience post-anoxic status epilepticus (PASE). Historically, PASE has been deemed untreatable resulting in its exclusion from status epilepticus clinical trials. However, emerging reports of survivors achieving functiona...

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Bibliographic Details
Main Authors: Carolina B. Maciel, Fernanda J. P. Teixeira, Katie J. Dickinson, Jessica C. Spana, Lisa H. Merck, Alejandro A. Rabinstein, Robert Sergott, Guogen Shan, Guanhong Miao, Charles A. Peloquin, Katharina M. Busl, Lawrence J. Hirsch
Format: Article
Language:English
Published: BMC 2022-01-01
Series:Neurological Research and Practice
Subjects:
Cardiac arrest
Heart arrest
Post-anoxic status epilepticus
GABA
Vigabatrin
Status epilepticus
Online Access:https://doi.org/10.1186/s42466-022-00168-x

Internet

https://doi.org/10.1186/s42466-022-00168-x

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