Impairment of Angiogenic Sphingosine Kinase-1/Sphingosine-1-Phosphate Receptors Pathway in Preeclampsia.

Preeclampsia (PE), is a serious pregnancy disorder characterized in the early gestation by shallow trophoblast invasion, impaired placental neo-angiogenesis, placental hypoxia and ischemia, which leads to maternal and fetal morbidity and mortality. Here we hypothesized that angiogenic sphingosine ki...

Full description

Bibliographic Details
Main Authors: Aneta Dobierzewska, Macarena Palominos, Marianela Sanchez, Michael Dyhr, Katja Helgert, Pia Venegas-Araneda, Stephen Tong, Sebastian E Illanes
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4902228?pdf=render