Inulin Induces IL-10 Secretion and Increased FOXP3 Gene Expression in Human Peripheral Blood Mononuclear Cells

ABSTRACT Inulin is an effective prebiotic and its potential in modulating systemic immunity have been proposed. A subpopulation of T cells, named T regulatory cells (Tregs), expressing the Forkhead boxP3 transcription factor are key mediators of peripheral tolerance and suppress undesirable immune r...

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Bibliographic Details
Main Authors: Marla Karine Amarante, Carolina Batista Ariza, Carlos Eduardo Coral de Oliveira, Karina de Almeida Gualtieri, Julie Massayo Maeda Oda, Maria Angelica Ehara Watanabe
Format: Article
Language:English
Published: Instituto de Tecnologia do Paraná (Tecpar) 2018-10-01
Series:Brazilian Archives of Biology and Technology
Subjects:
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132018000100417&lng=en&tlng=en