Maternal Flt-1 and endoglin expression by circulating monocyte subtype and polarization in preeclampsia and fetal growth restriction

Objective: Circulating levels of the anti-angiogenic factors sFlt-1 and sEndoglin are elevated in preeclampsia (PE) and fetal growth restriction (FGR), mainly secreted from placental trophoblast. This study aims to identify the contributory role of monocyte Flt-1 and endoglin expression in PE and FG...

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Bibliographic Details
Main Authors: Thushari Indika Alahakoon, Heather Medbury, Helen Williams, Nicole Fewings, Xin Wang, Vincent Lee
Format: Article
Language:English
Published: Elsevier 2019-07-01
Series:European Journal of Obstetrics & Gynecology and Reproductive Biology: X
Online Access:http://www.sciencedirect.com/science/article/pii/S2590161319300596