Cholesterol in the ciliary membrane as a therapeutic target against cancer

Primary cilium is a non-motile, antenna-like structure that develops in the quiescent G0 phase-cell surface. It is composed of an array of axonemal microtubules polymerized from the centrosome/basal body. The plasma membrane surrounding the primary cilium, which is called the ciliary membrane, conta...

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Bibliographic Details
Main Authors: Sotai Kimura, Tomoka Morita, Kosuke Hosoba, Hiroshi Itoh, Takashi Yamamoto, Tatsuo Miyamoto
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-03-01
Series:Frontiers in Molecular Biosciences
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fmolb.2023.1160415/full