Comparative Proteomics of Outer Membrane Vesicles from Polymyxin-Susceptible and Extremely Drug-Resistant Klebsiella pneumoniae

Comparative Proteomics of Outer Membrane Vesicles from Polymyxin-Susceptible and Extremely Drug-Resistant Klebsiella pneumoniae

ABSTRACT Outer membrane vesicles (OMVs) secreted by Gram-negative bacteria serve as transporters for the delivery of cargo such as virulence and antibiotic resistance factors. OMVs play a key role in the defense against membrane-targeting antibiotics such as the polymyxin B. Herein, we conducted com...

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Bibliographic Details
Main Authors: Maytham Hussein, Raad Jasim, Hakan Gocol, Mark Baker, Varsha J. Thombare, James Ziogas, Aayush Purohit, Gauri G. Rao, Jian Li, Tony Velkov
Format: Article
Language:English
Published: American Society for Microbiology 2023-02-01
Series:mSphere
Subjects:
polymyxin B
OMVs
proteomics
MDR Gram-negative
Online Access:https://journals.asm.org/doi/10.1128/msphere.00537-22

Internet

https://journals.asm.org/doi/10.1128/msphere.00537-22

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