Small molecules, inhibitors of DNA-PK, targeting DNA repair and beyond

Small molecules, inhibitors of DNA-PK, targeting DNA repair and beyond

Many current chemotherapies function by damaging genomic DNA in rapidly dividing cells ultimately leading to cell death. This therapeutic approach differentially targets cancer cells that generally display rapid cell division compared to normal tissue cells. However, although these treatments are i...

Full description

Bibliographic Details
Main Authors: David eDavidson, Lilian eAmrein, Lawrence ePanasci, Raquel eAloyz
Format: Article
Language:English
Published: Frontiers Media S.A. 2013-01-01
Series:Frontiers in Pharmacology
Subjects:
DNA Damage
DNA Repair
DNA-PKcs
DNAPK
DNA-PK inhibitors
Online Access:http://journal.frontiersin.org/Journal/10.3389/fphar.2013.00005/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fphar.2013.00005/full

Similar Items