Altered expression pattern of immune response-related genes and isoforms in hypersensitivity pneumonitis lung fibroblasts

Altered expression pattern of immune response-related genes and isoforms in hypersensitivity pneumonitis lung fibroblasts

Abstract Hypersensitivity pneumonitis (HP) is an immune-mediated inflammatory interstitial lung disease that may evolve to pulmonary fibrosis, a progressive disorder with a poor prognosis characterized by fibroblast activation and extracellular matrix accumulation. In HP lung fibroblasts, the gene e...

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Bibliographic Details
Main Authors: Ana Lilia Torres-Machorro, Carina Becerril, Everardo Hernández-Plata, Erika Rubí Luis-García, Mariel Maldonado, Iliana Herrera, Miguel Negreros, Fernando Hernández-Sánchez, Criselda Mendoza-Milla, Miguel Gaxiola, Remedios Ramírez, Annie Pardo, Ivette Buendía-Roldán, Moisés Selman, José Cisneros
Format: Article
Language:English
Published: Nature Portfolio 2024-10-01
Series:Scientific Reports
Subjects:
Hypersensitivity pneumonitis
mRNA splicing isoforms
IFI27
PDGFRA
AGER
α-SMA
Online Access:https://doi.org/10.1038/s41598-024-74267-x

Internet

https://doi.org/10.1038/s41598-024-74267-x

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