Endoplasmic Reticulum Stress Induced Proliferation Remains Intact in Aging Mouse β-Cells

Aging is associated with loss of proliferation of the insulin-secreting β-cell, a possible contributing factor to the increased prevalence of type 2 diabetes in the elderly. Our group previously discovered that moderate endoplasmic reticulum (ER) stress occurring during glucose exposure increases th...

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Bibliographic Details
Main Authors: Jarin T. Snyder, Christine Darko, Rohit B. Sharma, Laura C. Alonso
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-08-01
Series:Frontiers in Endocrinology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fendo.2021.734079/full