Engineered heart tissue maturation inhibits cardiomyocyte proliferative response to cryoinjury

The cellular and molecular mechanisms that are responsible for the poor regenerative capacity of the adult heart after myocardial infarction (MI) are still unclear and their understanding is crucial to develop novel regenerative therapies. Considering the lack of reliable in vitro tissue-like models...

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Bibliographic Details
Main Authors: Giulio Ciucci, Karim Rahhali, Giovanni Cimmino, Francesco Natale, Paolo Golino, Gianfranco Sinagra, Chiara Collesi, Francesco S Loffredo
Format: Article
Language:English
Published: SAGE Publishing 2023-10-01
Series:Journal of Tissue Engineering
Online Access:https://doi.org/10.1177/20417314231190147