Galectin 7 leads to a relative reduction in CD4+ T cells, mediated by PD-1

Abstract The role of glycan-binding proteins as an activator of immune regulatory receptors has gained attention recently. We report that galectin 7 reduced CD4+ T cell percentage in both in vitro culture and mouse tumor models. Immunohistochemical staining of esophageal cancer patient samples showe...

Full description

Bibliographic Details
Main Authors: Guojin Wu, Wei Deng, Hsin-Yi Chen, Hye-Jeong Cho, Jaehyup Kim
Format: Article
Language:English
Published: Nature Portfolio 2024-03-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-024-57162-3