Viral DNA Replication Orientation and hnRNPs Regulate Transcription of the Human Papillomavirus 18 Late Promoter

Viral DNA Replication Orientation and hnRNPs Regulate Transcription of the Human Papillomavirus 18 Late Promoter

ABSTRACT The life cycle of human papillomaviruses (HPVs) is tightly linked to keratinocyte differentiation. Although expression of viral early genes is initiated immediately upon virus infection of undifferentiated basal cells, viral DNA amplification and late gene expression occur only in the mid t...

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Bibliographic Details
Main Authors: Xiaohong Wang, Haibin Liu, Hui Ge, Masahiko Ajiro, Nishi R. Sharma, Craig Meyers, Pavel Morozov, Thomas Tuschl, Amar Klar, Donald Court, Zhi-Ming Zheng
Format: Article
Language:English
Published: American Society for Microbiology 2017-07-01
Series:mBio
Subjects:
DNA replication
HPV18
human papillomaviruses
gene expression
promoters
small RNAs
Online Access:https://journals.asm.org/doi/10.1128/mBio.00713-17

Internet

https://journals.asm.org/doi/10.1128/mBio.00713-17

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