Solvent bar microextraction combined with HPLC-DAD and multivariate optimization for simultaneous determination of three antiarrhythmic drugs in human urine and plasma samples

Solvent bar microextraction combined with HPLC-DAD and multivariate optimization for simultaneous determination of three antiarrhythmic drugs in human urine and plasma samples

A sensitive and simple microextraction approach was developed and validated to simultaneously determine three antiarrhythmic drugs, propranolol, diltiazem, and verapamil, in human urine and plasma samples, by combining solvent bar microextraction (SBME) with high-performance-liquid- chromatography d...

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Bibliographic Details
Main Authors: Nabil N. AL-Hashimi, Yahya S. Al-Degs, Enaam M.A. Al Momany, Amjad H. El-Sheikh, Abdelrahim M.A. Alqudah, Muna K.A. Oqal, Jafar I. Abdelghani
Format: Article
Language:English
Published: Elsevier 2022-12-01
Series:Talanta Open
Subjects:
Solvent bar microextraction
Antiarrhythmic drugs
Central composite design
HPLC-DAD
Urine and plasma
Online Access:http://www.sciencedirect.com/science/article/pii/S2666831922000571

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http://www.sciencedirect.com/science/article/pii/S2666831922000571

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