Structure–Activity relationship (SAR) of 18β-glycyrrhetinic acid derivatives on their antitumor activity through the PPARγ receptor and caspase-3 pathway

Structure–Activity relationship (SAR) of 18β-glycyrrhetinic acid derivatives on their antitumor activity through the PPARγ receptor and caspase-3 pathway

Licorice is extensively utilized in the food industry, and glycyrrhetinic acid is among the most critical active constituents in licorice. This ingredient has garnered increasing attention in recent years. In a previous study, we identified a new series of Glycyrrhetinic acid derivatives containing...

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Bibliographic Details
Main Authors: Juan Sun, Qi Zheng, Yi-Heng Zhang, Cai-Shi Liu, Chong-Hao Chen, Shao-Peng Yan, Xiao-Meng Guo, Su-Pei Hu, Yang Zhou, Yuan-Feng Wu
Format: Article
Language:English
Published: Elsevier 2024-03-01
Series:Journal of Saudi Chemical Society
Subjects:
Glycyrrhetinic acid
PPARγ
Molecular docking
Antitumor
Online Access:http://www.sciencedirect.com/science/article/pii/S1319610324000103

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http://www.sciencedirect.com/science/article/pii/S1319610324000103

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