Optimizing the Seeding Density of Human Mononuclear Cells to Improve the Purity of Highly Proliferative Mesenchymal Stem Cells

Mesenchymal stem cells (MSCs) hold considerable promise for regenerative medicine. Optimization of the seeding density of mononuclear cells (MNCs) improves the proliferative and differentiation potential of isolated MSCs. However, the underlying mechanism is unclear. We cultured human bone marrow MN...

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Bibliographic Details
Main Authors: Hiroyuki Nagai, Akihiro Miwa, Kenji Yoneda, Koichi Fujisawa, Taro Takami
Format: Article
Language:English
Published: MDPI AG 2023-01-01
Series:Bioengineering
Subjects:
Online Access:https://www.mdpi.com/2306-5354/10/1/102