Immunogenicity of influenza vaccine in elderly people: a systematic review and meta-analysis of randomized controlled trials, and its association with real-world effectiveness

Background: Older people (≥60 years old) are particularly vulnerable to influenza virus infection, and vaccine is effective in reducing the disease burden in this population. However, it remains obscure whether their antibody response is lower than those of younger adults (18–60 years old). Thus, th...

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Bibliographic Details
Main Authors: Ziyan Meng, Jiayou Zhang, Jinrong Shi, Wei Zhao, Xiaoyuan Huang, Li Cheng, Xiaoming Yang
Format: Article
Language:English
Published: Taylor & Francis Group 2020-11-01
Series:Human Vaccines & Immunotherapeutics
Subjects:
Online Access:http://dx.doi.org/10.1080/21645515.2020.1747375