Substantially Modified Ratios of Effector to Regulatory T Cells During Chemotherapy in Ovarian Cancer Patients Return to Pre-Treatment Levels at Completion: Implications for Immunotherapy

Substantially Modified Ratios of Effector to Regulatory T Cells During Chemotherapy in Ovarian Cancer Patients Return to Pre-Treatment Levels at Completion: Implications for Immunotherapy

Ovarian cancer is the leading cause of death from gynaecological malignancy. Despite improved detection and treatment options, relapse rates remain high. Combining immunotherapy with the current standard treatments may provide an improved prognosis, however, little is known about how standard chemot...

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Bibliographic Details
Main Authors: Magdalena Plebanski, Karen Scalzo-Inguanti, Sue D. Xiang, Michael Quinn, Julene Halo, Chindu Govindaraj, Anthony Park
Format: Article
Language:English
Published: MDPI AG 2012-06-01
Series:Cancers
Subjects:
CD4+ T cells
CD8 T cells
regulatory T cells
ovarian cancer
Online Access:http://www.mdpi.com/2072-6694/4/2/581

Internet

http://www.mdpi.com/2072-6694/4/2/581

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