Characterization of APOBEC3 variation in a population of HIV-1 infected individuals in northern South Africa

Characterization of APOBEC3 variation in a population of HIV-1 infected individuals in northern South Africa

Abstract Background The apolipoprotein B mRNA-editing enzyme, catalytic polypeptide-like 3 (APOBEC3) genes A3D, A3F, A3G and A3H have all been implicated in the restriction of human immunodeficiency virus type 1 (HIV-1) replication. Polymorphisms in these genes are likely to impact viral replication...

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Bibliographic Details
Main Authors: Nontokozo D. Matume, Denis M. Tebit, Laurie R. Gray, Stephen D. Turner, David Rekosh, Pascal O. Bessong, Marie-Louise Hammarskjöld
Format: Article
Language:English
Published: BMC 2019-01-01
Series:BMC Medical Genetics
Subjects:
APOBEC3
Single nucleotide polymorphism
South Africa
Online Access:http://link.springer.com/article/10.1186/s12881-018-0740-4

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http://link.springer.com/article/10.1186/s12881-018-0740-4

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