Multimodal MRI Longitudinal Assessment of White and Gray Matter in Different SPG Types of Hereditary Spastic Paraparesis

Multimodal MRI Longitudinal Assessment of White and Gray Matter in Different SPG Types of Hereditary Spastic Paraparesis

Hereditary spastic paraplegias (HSP) are a group of genetically and clinically heterogeneous neurologic disorders. Hereby we describe a relatively large group of patients (pts) affected by HSP studied at baseline (31 pts) and at follow-up (mean period 28.9 ± 8.4 months; 23 pts) with multimodal advan...

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Bibliographic Details
Main Authors: Domenico Montanaro, M. Vavla, F. Frijia, G. Aghakhanyan, A. Baratto, A. Coi, C. Stefan, G. Girardi, G. Paparella, S. De Cori, P. Totaro, F. Lombardo, G. Piccoli, Andrea Martinuzzi
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-06-01
Series:Frontiers in Neuroscience
Subjects:
HSP
hereditary spastic paraplegia
MRS – 1H nuclear magnetic resonance spectra
VBM
voxel-based morphometry
DTI (diffusion tensor imaging)
Online Access:https://www.frontiersin.org/article/10.3389/fnins.2020.00325/full

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https://www.frontiersin.org/article/10.3389/fnins.2020.00325/full

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