Somatic targeted mutation profiling of colorectal cancer precursor lesions

Somatic targeted mutation profiling of colorectal cancer precursor lesions

Abstract Background Most colorectal cancers (CRC) arise from precursor lesions. This study aimed to characterize the mutation profile of colorectal cancer precursor lesions in a Brazilian population. Methods In total, 90 formalin-fixed paraffin-embedded colorectal precursor lesions, including 67 ade...

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Bibliographic Details
Main Authors: Wellington dos Santos, Mariana Bisarro dos Reis, Jun Porto, Ana Carolina de Carvalho, Marcus Matsushita, Gabriela Oliveira, Kari Syrjänen, Rui Manuel Reis, Denise Peixoto Guimarães
Format: Article
Language:English
Published: BMC 2022-06-01
Series:BMC Medical Genomics
Subjects:
Screening
Adenoma
Serrated polyps
Mutation
Molecular profiling
Brazil
Online Access:https://doi.org/10.1186/s12920-022-01294-w

Internet

https://doi.org/10.1186/s12920-022-01294-w

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