Paxillin participates in the sphingosylphosphorylcholine-induced abnormal contraction of vascular smooth muscle by regulating Rho-kinase activation

Paxillin participates in the sphingosylphosphorylcholine-induced abnormal contraction of vascular smooth muscle by regulating Rho-kinase activation

Abstract Background The Ca2+-independent contraction of vascular smooth muscle is a leading cause of cardiovascular and cerebrovascular spasms. In the previous study, we demonstrated the involvement of Src family protein tyrosine kinase Fyn and Rho-kinase in the sphingosylphosphorylcholine (SPC)-ind...

Full description

Bibliographic Details
Main Authors: Ying Zhang, Nan Li, Sei Kobayashi
Format: Article
Language:English
Published: BMC 2024-01-01
Series:Cell Communication and Signaling
Subjects:
Sphingosylphosphorylcholine
Vascular smooth muscle cell
Vascular contraction
Paxillin
Fyn
Rho-kinase
Online Access:https://doi.org/10.1186/s12964-023-01404-w

Internet

https://doi.org/10.1186/s12964-023-01404-w

Similar Items