Drug-induced regulation of target expression.

Drug-induced regulation of target expression.

Drug perturbations of human cells lead to complex responses upon target binding. One of the known mechanisms is a (positive or negative) feedback loop that adjusts the expression level of the respective target protein. To quantify this mechanism systems-wide in an unbiased way, drug-induced differen...

Bibliografski detalji
Glavni autori:	Murat Iskar, Monica Campillos, Michael Kuhn, Lars Juhl Jensen, Vera van Noort, Peer Bork
Format:	Članak
Jezik:	English
Izdano:	Public Library of Science (PLoS) 2010-09-01
Serija:	PLoS Computational Biology
Online pristup:	https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/20838579/pdf/?tool=EBI

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