Drug-induced regulation of target expression.
Drug perturbations of human cells lead to complex responses upon target binding. One of the known mechanisms is a (positive or negative) feedback loop that adjusts the expression level of the respective target protein. To quantify this mechanism systems-wide in an unbiased way, drug-induced differen...
| Hlavní autoři: | , , , , , |
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| Médium: | Článek |
| Jazyk: | English |
| Vydáno: |
Public Library of Science (PLoS)
2010-09-01
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| Edice: | PLoS Computational Biology |
| On-line přístup: | https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/20838579/pdf/?tool=EBI |