Local transmural action potential gradients are absent in the isolated, intact dog heart but present in the corresponding coronary‐perfused wedge

Abstract The left ventricular (LV) coronary‐perfused canine wedge preparation is a model commonly used for studying cardiac repolarization. In wedge studies, transmembrane potentials typically are recorded; whereas, extracellular electrical recordings are commonly used in intact hearts. We compared...

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Bibliographic Details
Main Authors: Bastiaan J. Boukens, Veronique M. F. Meijborg, Charly N. Belterman, Tobias Opthof, Michiel J. Janse, Richard B. Schuessler, Ruben Coronel, Igor R. Efimov
Format: Article
Language:English
Published: Wiley 2017-05-01
Series:Physiological Reports
Subjects:
Online Access:https://doi.org/10.14814/phy2.13251