Integrated tumor genomic and immune microenvironment analysis identifies predictive biomarkers associated with the efficacy of neoadjuvant therapy for triple‐negative breast cancer

Integrated tumor genomic and immune microenvironment analysis identifies predictive biomarkers associated with the efficacy of neoadjuvant therapy for triple‐negative breast cancer

Abstract Background Although neoadjuvant chemotherapy (NAC) is currently the best therapy for triple‐negative breast cancer (TNBC), resistance still occurs in a considerable proportion, thus it is crucial to understand resistance mechanisms and identify predictive biomarkers for patients selection....

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Bibliographic Details
Main Authors: Yanhui Zhu, Hongfei Zhang, Chaohu Pan, Gao He, Xiaoli Cui, Xiafei Yu, Xiaoqiang Zhang, Dongfang Wu, Junzhe Yang, Xian Wu, Haitao Luo, Xiaoan Liu
Format: Article
Language:English
Published: Wiley 2023-03-01
Series:Cancer Medicine
Subjects:
biomarkers
breast cancer
CD8 T cells
M2 macrophages
neoadjuvant chemotherapy therapy
TMB
Online Access:https://doi.org/10.1002/cam4.5372

Internet

https://doi.org/10.1002/cam4.5372

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