Retinal Glial Cells in Von Hippel–Lindau Disease: A Novel Approach in the Pathophysiology of Retinal Hemangioblastoma

Background: Von Hippel–Lindau (VHL) disease is a neoplastic syndrome caused by a mutation of the VHL tumor suppressor gene. Retinal hemangioblastoma (RH) is a vascularized tumor and represents the most common ocular manifestation of this disease. At the retinal level, VHL protein is able to regulate...

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Bibliographic Details
Main Authors: Elisabetta Pilotto, Giulia Midena, Tommaso Torresin, Gilda De Mojà, Maria Laura Bacelle, Alfonso Massimiliano Ferrara, Stefania Zovato, Edoardo Midena
Format: Article
Language:English
Published: MDPI AG 2021-12-01
Series:Cancers
Subjects:
Online Access:https://www.mdpi.com/2072-6694/14/1/170