Role of T198 modification in the regulation of p27(Kip1) protein stability and function.

The tumor suppressor gene p27(Kip1) plays a fundamental role in human cancer progression. Its expression and/or functions are altered in almost all the different tumor histotype analyzed so far. Recently, it has been demonstrated that the tumor suppression function of p27 resides not only in the abi...

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Bibliographic Details
Main Authors: Monica Schiappacassi, Sara Lovisa, Francesca Lovat, Linda Fabris, Alfonso Colombatti, Barbara Belletti, Gustavo Baldassarre
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-03-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/21423803/?tool=EBI