Pupil Dynamics Reflect Behavioral Choice and Learning in a Go/NoGo Tactile Decision-Making Task in Mice

The eye’s pupil undergoes dynamic changes in diameter associated with cognitive effort, motor activity, and emotional state, and can be used to index brain state across mammalian species. Recent studies in head-fixed mice have linked arousal-related pupil dynamics with global neural activity as well...

Full description

Bibliographic Details
Main Authors: Christian R Lee, David J Margolis
Format: Article
Language:English
Published: Frontiers Media S.A. 2016-11-01
Series:Frontiers in Behavioral Neuroscience
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fnbeh.2016.00200/full