An intact centrosome is required for the maintenance of polarization during directional cell migration.

Establishing and maintaining polarization is critical during cell migration. It is known that the centrosome contains numerous proteins whose roles of organizing the microtubule network range include nucleation, stabilization and severing. It is not known whether the centrosome is necessary to maint...

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Bibliographic Details
Main Authors: Nicole M Wakida, Elliot L Botvinick, Justin Lin, Michael W Berns
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-12-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3009746?pdf=render