Proteotyping of knockout mouse strains reveals sex- and strain-specific signatures in blood plasma

Proteotyping of knockout mouse strains reveals sex- and strain-specific signatures in blood plasma

Abstract We proteotyped blood plasma from 30 mouse knockout strains and corresponding wild-type mice from the International Mouse Phenotyping Consortium. We used targeted proteomics with internal standards to quantify 375 proteins in 218 samples. Our results provide insights into the manifested effe...

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Bibliographic Details
Main Authors: Yassene Mohammed, Sarah A. Michaud, Helena Pětrošová, Juncong Yang, Milan Ganguly, David Schibli, Ann M. Flenniken, Lauryl M. J. Nutter, Hibret A. Adissu, K. C. Kent Lloyd, Colin McKerlie, Christoph H. Borchers
Format: Article
Language:English
Published: Nature Portfolio 2021-05-01
Series:npj Systems Biology and Applications
Online Access:https://doi.org/10.1038/s41540-021-00184-8

Internet

https://doi.org/10.1038/s41540-021-00184-8

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