BIBR1532 inhibits proliferation and enhances apoptosis in multiple myeloma cells by reducing telomerase activity

Background Multiple myeloma (MM) is a rare haematological disorder with few therapeutic options. BIBR1532, a telomerase inhibitor, is widely used in cancer treatment and has promising outcomes. In this study, we investigated the efficacy and mechanism of action of BIBR1532 in MM. Methods K562 and ME...

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Bibliographic Details
Main Authors: Yuefeng Zhang, Xinxin Yang, Hangqun Zhou, Guoli Yao, Li Zhou, Chunyan Qian
Format: Article
Language:English
Published: PeerJ Inc. 2023-11-01
Series:PeerJ
Subjects:
Online Access:https://peerj.com/articles/16404.pdf