Neuronal Nuclear Membrane Budding Occurs during a Developmental Window Modulated by Torsin Paralogs

DYT1 dystonia is a neurodevelopmental disease that manifests during a discrete period of childhood. The disease is caused by impaired function of torsinA, a protein linked to nuclear membrane budding. The relationship of NE budding to neural development and CNS function is unclear, however, obscurin...

Full description

Bibliographic Details
Main Authors: Lauren M. Tanabe, Chun-Chi Liang, William T. Dauer
Format: Article
Language:English
Published: Elsevier 2016-09-01
Series:Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124716311111