Dual inhibitors of DNMT and HDAC induce viral mimicry to induce antitumour immunity in breast cancer

Dual inhibitors of DNMT and HDAC induce viral mimicry to induce antitumour immunity in breast cancer

Abstract The existing conventional treatments for breast cancer, including immune checkpoint blockade, exhibit limited effects in some cancers, particularly triple-negative breast cancer. Epigenetic alterations, specifically DNMT and HDAC alterations, are implicated in breast cancer pathogenesis. We...

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Bibliographic Details
Main Authors: Wenjun Huang, Qingyun Zhu, Zhichao Shi, Yao Tu, Qinyuan Li, Wenwen Zheng, Zigao Yuan, Lulu Li, Xuyu Zu, Yue Hao, Bizhu Chu, Yuyang Jiang
Format: Article
Language:English
Published: Nature Publishing Group 2024-03-01
Series:Cell Death Discovery
Online Access:https://doi.org/10.1038/s41420-024-01895-7

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https://doi.org/10.1038/s41420-024-01895-7

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