Identification and characterization of the anti-SARS-CoV-2 activity of cationic amphiphilic steroidal compounds

Identification and characterization of the anti-SARS-CoV-2 activity of cationic amphiphilic steroidal compounds

The ongoing COVID-19 pandemic caused a significant loss of human lives and a worldwide decline in quality of life. Treatment of COVID-19 patients is challenging, and specific treatments to reduce COVID-19 aggravation and mortality are still necessary. Here, we describe the discovery of a novel class...

Full description

Bibliographic Details
Main Authors: Alexandre Borin, Laís D. Coimbra, Karina Bispo-dos-Santos, Fabrício F. Naciuk, Marina Fontoura, Camila L. Simeoni, Giovanni F. Gomes, Mariene R. Amorim, Humberto D. Gravina, Jacqueline Farinha Shimizu, Amanda S. C. Passos, Isadora M. de Oliveira, Ana Carolina de Carvalho, Alisson Campos Cardoso, Pierina L. Parise, Daniel A. Toledo-Teixeira, Giuliana E. Sotorilli, Gabriela F. Persinoti, Ingra Morales Claro, Ester C. Sabino, Marcos R. Alborghetti, Silvana A. Rocco, Kleber G. Franchini, William M. de Souza, Paulo S. L. Oliveira, Thiago M. Cunha, Fabiana Granja, José Luiz Proença-Módena, Daniela B.B. Trivella, Marjorie Bruder, Artur T. Cordeiro, Rafael Elias Marques
Format: Article
Language:English
Published: Taylor & Francis Group 2022-12-01
Series:Virulence
Subjects:
SARS-CoV-2
drug discovery
steroidal compounds
antiviral activity
Online Access:https://www.tandfonline.com/doi/10.1080/21505594.2022.2085793

Internet

https://www.tandfonline.com/doi/10.1080/21505594.2022.2085793

Similar Items