Decreases in GSH:GSSG activate vascular endothelial growth factor receptor 2 (VEGFR2) in human aortic endothelial cells

The angiogenic capacity of local tissue critically regulates the response to ischemic injury. Elevated reactive oxygen species production, commonly associated with ischemic injury, has been shown to promote phosphorylation of the vascular endothelial growth factor receptor 2 (VEGFR2), a critical reg...

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Bibliographic Details
Main Authors: Priya K. Prasai, Bandana Shrestha, A. Wayne Orr, Christopher B. Pattillo
Format: Article
Language:English
Published: Elsevier 2018-10-01
Series:Redox Biology
Online Access:http://www.sciencedirect.com/science/article/pii/S2213231718303744