Are carfentanil and acrylfentanyl naloxone resistant?

The rapid rise in deaths since 2012 due to opioid poisoning is correlated with the proliferation of potent synthetic opioid agonists such as fentanyl, acrylfentanyl, and carfentanil. The efficacy of frontline antidotes such as naloxone in reversing such poisoning events has been questioned, and the...

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Bibliographic Details
Main Authors: Michael G. Feasel, Theodore S. Moran, Boyle C. Cheng, Saadyah Averick
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-02-01
Series:Frontiers in Psychiatry
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fpsyt.2024.1359851/full