Mitochondrial respiration--an important therapeutic target in melanoma.

The importance of mitochondria as oxygen sensors as well as producers of ATP and reactive oxygen species (ROS) has recently become a focal point of cancer research. However, in the case of melanoma, little information is available to what extent cellular bioenergetics processes contribute to the pro...

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Bibliographic Details
Main Authors: Michelle Barbi de Moura, Garret Vincent, Shelley L Fayewicz, Nicholas W Bateman, Brian L Hood, Mai Sun, Joseph Suhan, Stefan Duensing, Yan Yin, Cindy Sander, John M Kirkwood, Dorothea Becker, Thomas P Conrads, Bennett Van Houten, Stergios J Moschos
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3422349?pdf=render