Characterizing RNA-binding ligands on structures, chemical information, binding affinity and drug-likeness

Recent studies suggest RNAs act as promising drug targets. However, limited development has been achieved in detecting RNA–ligand interactions. To guide the discovery of RNA-binding ligands, it is necessary to characterize them comprehensively, especially in the binding specificity, binding affinity...

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Bibliographic Details
Main Authors: Cong Fan, Xin Wang, Tianze Ling, Yuedong Yang, Huiying Zhao
Format: Article
Language:English
Published: Taylor & Francis Group 2023-12-01
Series:RNA Biology
Subjects:
Online Access:http://dx.doi.org/10.1080/15476286.2023.2231708