Bupleurum marginatum Wall.ex DC in Liver Fibrosis: Pharmacological Evaluation, Differential Proteomics, and Network Pharmacology

Liver fibrosis is a common pathological feature of many chronic liver diseases. Bupleurum marginatum Wall.ex DC (ZYCH) is a promising therapeutic for liver fibrosis. In this study, 25 compounds were isolated from ZYCH, and the effects of ZYCH on DMN-induced liver fibrosis in rats were evaluated. The...

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Bibliographic Details
Main Authors: Xiujie Liu, Yu Shi, Yinghui Hu, Ke Luo, Ying Guo, Weiwei Meng, Yulin Deng, Rongji Dai
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-05-01
Series:Frontiers in Pharmacology
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Online Access:http://journal.frontiersin.org/article/10.3389/fphar.2018.00524/full