Mammalian target of rapamycin activity is required for expansion of CD34+ hematopoietic progenitor cells
Background The mammalian target of rapamycin is a conserved protein kinase known to regulate protein synthesis, cell size and proliferation. Aberrant regulation of mammalian target of rapamycin activity has been observed in hematopoietic malignancies, including acute leukemias and myelodysplastic sy...
| Main Authors: | , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Ferrata Storti Foundation
2009-07-01
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| Series: | Haematologica |
| Online Access: | https://haematologica.org/article/view/5298 |