The transcriptome landscape of 3D-cultured placental trophoblasts reveals activation of TLR2 and TLR3/7 in response to low Trypanosoma cruzi parasite exposure
Vertical transmission of Trypanosoma cruzi (T. cruzi) become a globalized health problem accounting for 22% of new cases of Chagas disease (CD). Congenital infection is now considered the main route of CD spread in non-endemic countries where no routine disease testing of pregnant women is implement...
Main Authors: | Erica Silberstein, Charles C. Chung, Alain Debrabant |
---|---|
Format: | Article |
Language: | English |
Published: |
Frontiers Media S.A.
2023-09-01
|
Series: | Frontiers in Microbiology |
Subjects: | |
Online Access: | https://www.frontiersin.org/articles/10.3389/fmicb.2023.1256385/full |
Similar Items
-
Human Placental Trophoblasts Are Resistant to Trypanosoma cruzi Infection in a 3D-Culture Model of the Maternal-Fetal Interface
by: Erica Silberstein, et al.
Published: (2021-03-01) -
Ex Vivo Infection of Human Placental Explants by <i>Trypanosoma cruzi</i> Reveals a microRNA Profile Similar to That Seen in Trophoblast Differentiation
by: Lisvaneth Medina, et al.
Published: (2022-03-01) -
Aleatory Trypanosoma cruzi Vertical Transmission in Chiapas, Mexico: A Case Report
by: Sury Antonio López-Cancino, et al.
Published: (2021-11-01) -
Effects of severe protein restriction in levels of parasitemia and in mortality of mice accutely infected with Trypanosoma cruzi
by: Nildete G.L. Gomes, et al.
Published: (1994-03-01) -
Vaccination with epimastigotes of different strains of Trypanosoma rangeli protects mice against Trypanosoma cruzi infection
by: Beatriz Basso, et al.
Published: (2008-06-01)