Novel NUDT15 germline variant in acute lymphoblastic leukaemia â Increase susceptibility to mercaptopurine toxicity responsible for relapse and severe life threatening sepsis: A case report
Acute lymphoblastic leukaemia (ALL) has become one of most curable malignancies among all childhood cancers. Such results are possible because of improved understanding of the biology and pathophysiology of the disease with discovery of novel mutations effecting the pharmacodynamics of the drugs. On...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Elsevier
2017-10-01
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| Series: | Pediatric Hematology Oncology Journal |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2468124517300803 |