Angiotensin I-converting enzyme (ACE) inhibition and nitric oxide (NO)-mediated antihypertensive effect of octaphlorethol A isolated from Ishige sinicola: In vitro molecular mechanism and in vivo SHR model

Angiotensin I-converting enzyme (ACE) inhibition and nitric oxide (NO)-mediated antihypertensive effect of octaphlorethol A isolated from Ishige sinicola: In vitro molecular mechanism and in vivo SHR model

Angiotensin I-converting enzyme (ACE) inhibition and nitric oxide (NO) production are important factors that regulate blood pressure. In this study, the effects of octaphlorethol A (OPA) isolated from Ishige sinicola on ACE inhibition and NO production, the molecular mechanism underlying ACE inhibit...

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Bibliographic Details
Main Authors: Seok-Chun Ko, Won-Kyo Jung, Sung-Myung Kang, Seung-Hong Lee, Min Cheol Kang, Soo-Jin Heo, Kyong-Hwa Kang, Yong-Tae Kim, Sun-Joo Park, Yoonhwa Jeong, Misook Kim, Hee-Guk Byun, You-Jin Jeon
Format: Article
Language:English
Published: Elsevier 2015-10-01
Series:Journal of Functional Foods
Subjects:
Octaphlorethol A (OPA)
Angiotensin I-converting enzyme (ACE)
Nitric oxide (NO)
Antihypertensive effect
Molecular mechanism
Online Access:http://www.sciencedirect.com/science/article/pii/S1756464615003618

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http://www.sciencedirect.com/science/article/pii/S1756464615003618

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