Development of copper-catalyzed deaminative esterification using high-throughput experimentation

Given their low cost and diverse nature, coupling of amine and carboxylic acid building blocks provides an opportunity to expand the accessible chemical space. Here, a copper-catalyzed deaminative esterification of aryl amines with carboxylic acids is developed and its use in library synthesis with...

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Bibliographic Details
Main Authors: Yuning Shen, Babak Mahjour, Tim Cernak
Format: Article
Language:English
Published: Nature Portfolio 2022-07-01
Series:Communications Chemistry
Online Access:https://doi.org/10.1038/s42004-022-00698-0