Development of copper-catalyzed deaminative esterification using high-throughput experimentation
Given their low cost and diverse nature, coupling of amine and carboxylic acid building blocks provides an opportunity to expand the accessible chemical space. Here, a copper-catalyzed deaminative esterification of aryl amines with carboxylic acids is developed and its use in library synthesis with...
Main Authors: | , , |
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Format: | Article |
Language: | English |
Published: |
Nature Portfolio
2022-07-01
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Series: | Communications Chemistry |
Online Access: | https://doi.org/10.1038/s42004-022-00698-0 |